There is nothing really to see or do near 128 station without a car unless you are working at one of the many business offices near by. It is an area of mostly office buildings near a major highway interchange. (It's a convenient location for people taking Amtrak and commuter rail from the south suburbs of Boston.)
The one thing that is there is very frequent commuter rail and Amtrak service to downtown Boston. A recent post mentioned there is a good, relatively inexpensive hotel a five minute walk from the station. (It must be just across the parking lot.)
It is a totally safe area.
If you are coming as a tourist, I think it would be much more convenient to be in downtown Boston, within walking distance of very many historic sites, museums, restaurants, the aquarium, subways, trolleys and buses to all over the city, ferries and scenic boat trips around or across the harbor or all the way to Provincetown on the tip of Cape Cod. You can get to all those things from Rt 128, but first you need to take a train into the city. (Maybe, if the hotels are enough cheaper, it would be worth the extra time, about 15 minutes, and cost to stay there and take the train in. But beware the last train to 128 is about 11PM on weekends, be sure to check the schedules!