I just got done commenting on a Quora question's answer where the answerer was griping about having to go all the way to DC from Tampa, FL (Amtrak bus to the Silver Meteor, Silver Meteor to DC, Crescent DC-NOLA) to catch the Crescent to NOLA. I did a quick search on the Amtrak website, and found an all-train routing which was faster and cheaper (Silver Star to Raleigh, NC, Carolinean to Greensboro, NC, then Crescent to NOLA). At least that complainer had options other than driving straight through or flying (which people in areas not served by Amtrak at all wouldn't have)!