Back when my daughter was little, we had a nebulizer to give her asthma medicine. So we decide to take a vacation to Grenada, where the current was 220V 50 Hz. I had the sense to get a voltage converter, but when we tried to use the nebulizer, the motor ran very sluggishly and couldn't nebulize anything. At least the volrage converter kept us from frying out the motor. Fortunately, the hotel contacted a local doctor for us, and we got a loan of a 220V 50 Hz nebulizer for the length of our stay.
Nowadays, it seems that most plug in appliances are actually DC, and the "wall warts" that you plug in will take anything from 110V to 240V nd convert tht to the proper DC voltage. I used my CPAP in China with no problem.