neroden
Engineer
With the benefit of local knowledge (cough cough) I can say that the cities along the Erie Canal Corridor, including Auburn, are solid enough that locating a business there could make a lot of sense. They still have skilled workforces and smart kids who are loyal enough that they are staying. And if they get the hankering to go to New York City... they can take the train. (And airfares are reasonable, too.)I see lots of Commercials on TV about incentives for locating New Businesses in Up-State New York and they show different types in such faded cities as Buffalo, Rochester, Utica, Syracuse etc.
The cities along the Susquehanna River corridor are another matter. Honestly, they've been declining since the Erie Canal opened The manufacturing knowledge is much more hollowed out and the whole area is going back to its farming roots. They're very isolated in transportation terms -- you gotta drive everywhere (no passenger trains, sky-high airfare and minimal flights), and the roads are slow and bad. It makes them a highly unattractive place for people to move.