I'm ranking intercity buses, if that is what you mean by "work". In that case, it's pretty simple. The D4500CT is inferior to both the H3-45 and X3-45 for intercity use. Sure, it's got the higher driver's seat and the lower window sill. But, overall, it's still worse than the H3-45 and X3-45.
I like a relaxing, daytime bus ride. Those are my favorite bus rides and those are the reason why I'd rather ride a bus than drive. When I drive, I can't relax, I have to pay attention. I like enjoying the scenery and I like the big windows and the splendid lines-of-sight offered by a DL3's low window sills. I'd love if the DL3 was still in production. That low window sill make a big difference to me, because cars never have that low of a window sill. That's just me. To each his own.
As for the vents, I'm going to have to peek inside them the next time I ride a Greyhound DL3. Still, if you go to 7:42 in that DL3 video I posted, you'll see that particular DL3 has completely empty, open parcel racks. No vents, no slits, no covers, just luggage space.