The DL-3's, they sent down (remember 978 and 979 especially), were 7-speeds. We never had those in our fleet, so it took quite a bit of practice to master. We had 4-speeds in our MC-9's that were very easy to shift. We did have a couple of 102C-3's with 5 speeds
The 7 speed had reverse way over to the left and up...first was down, and it was a very low 'granny gear' that you could normally not use unless starting with a heavy load on a steep hill....you would just about get moving, and it was time to shift to second,,,if you were not quick, you would lose momentum and have to slip the clutch to avoid stalling out.
From the neutral position, second was slightly left and up, third slightly left and down, fourth slightly right and up, fifth slightly right and down, sixth way over to the right and up, and seventh way over to the right and down..... you really had to push against a spring to reach reverse and first, and also to reach sixth and seventh. 2, 3, 4, and 5 were in a tight pattern in the center, and it was easy to mistake 2&4 or 3&5 until experienced.
So yes, while I would not want to have to constantly have to depress the clutch in heavy Lincoln Tunnel stop and go traffic, it was a challenge to learn to properly shift the 7 speed, and since by then all our 'sticks' were gone, it was enjoyable and satisfying to drive a manual occasionally....especially when a new driver couldn't drive it , and you got to 'show off' your skills....
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Being in the proper gear ratio does have an impact on fuel economy....the engine operates most efficiently when in a certain speed range (RPM), and that will take being in the proper gear ratio at a given road speed...It's pretty hard for a human to beat a computer controlled automated manual at that task, except perhaps on a hilly highway, where the human can 'see' the ups and downs in advance and take advantage of that knowledge...
One interesting thing about those 7 speeds....even though fully manual, the engine ECU would limit RPM's in the lowest gears, forcing the driver to upshift earlier than the normal 'red line' for improved fuel economy....